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144. Targeting KRAS Diversity: Covalent Modulation of G12X and Beyond in Cancer Therapy T. Kirschner, M. P. Müller and D. Rauh J. Med. Chem. 2024 67 (8) 6044-6051
Mar 4, 2025 · Drug Discovery Hub Dortmund: The mission of the DDHD is translating basic academic research into pharmaceutical application. In an approach that is by nature highly transdisciplinary, …
Research The development of new medicines is a very long and complex process. It starts with the initial target identification and validation, followed by assay development. High throughput screening …
TU Dortmund Prof. Dr. Daniel Rauh started his independent research career in Dortmund in 2006. Research in his lab is dedicated to medicinal chemistry, compound screening technologies and …
MPI / COMAS In the department of Chemical Biology at the Max Planck Institute of Molecular Physiology (MPI) Prof. Dr. Dr. h.c. Herbert Waldmann successfully develops new strategies for the …
New Publication: Akt Isoform-Selective Inhibitors featured in Nature Communications The combination of structure-based design, biochemical characterization, and a novel and innovative cell system …
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